Dr. Charles C. Esenwa
Founder & Chief Medical Officer — SMARTS HealthDr. Esenwa is a nationally recognized neurologist and stroke prevention authority whose work centers on redesigning cardiovascular and brain health systems toward earlier detection, equitable prevention, and long-term risk control.
As the founding clinical architect of SMARTS Health, he defines the medical governance, screening pathways, and evidence-based monitoring protocols that power the platform's preventive care model.
Top 10 Publications
Selected from more than 70 peer-reviewed publications, these works span stroke risk stratification, inflammation and vascular risk, structural determinants of cerebrovascular disease, and the design of preventive systems of care.
- Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke
- Stroke Risk Factors, Genetics, and Prevention
- Historical Slavery and Modern-Day Stroke Mortality in the United States Stroke Belt
- Historical Redlining, Social Determinants of Health, and Stroke Prevalence in Communities in New York City
- Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting
- Secondary Stroke Prevention: Challenges and Solutions
- Biomarkers of Coagulation and Inflammation in COVID-19-Associated Ischemic Stroke
- The Effect of COVID-19 on Stroke Hospitalizations in New York City
- Transforming Posthospital Stroke Care, Outcomes, and Use of New Innovations Through Implementation Science
- Prevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis
Full publication record available on PubMed.
Clinical Leadership
Dr. Esenwa directs comprehensive stroke systems serving complex urban populations, leading acute care coordination, quality improvement initiatives, and longitudinal prevention strategy redesign.
Preventive Strategy
His preventive frameworks emphasize early detection of silent cardiovascular risk factors, scalable monitoring infrastructure, and clinically guided digital interventions for high-risk individuals.
Medical Governance at SMARTS
Dr. Esenwa ensures that SMARTS Health operates as a clinically defensible medical platform by supervising regulatory alignment, patient safety standards, and clinical evidence integration.
Core Expertise
Vascular neurology, acute stroke systems of care, cardiovascular risk stratification, public health strategy, remote patient monitoring, preventive brain health.